The 90-Day Protocol for Vascular Age Reversal

Most people assume that once vascular function starts to decline, the best you can do is slow it down. Manage it with medication and accept that this is what aging looks like.

That assumption is wrong, and it's costing you years of performance you could otherwise have.

Vascular Function Is Not A Fixed State

The endothelium, which is the layer of cells lining every blood vessel in your body, is not static tissue. It regenerates. It responds to signals. And when given the right inputs, it can recover function that was previously lost.

The glycocalyx, which sits on top of the endothelium, works the same way. It can be stripped down by chronic stress and poor metabolic conditions, but it can also be rebuilt when those conditions change. The research on sulfated polysaccharides, particularly rhamnan sulfate, has shown measurable regeneration of the glycocalyx in as little as eight weeks.

This is observable in the biomarkers.

Why Generic Lifestyle Advice Doesn't Cut It

You've probably already tried to address some of this yourself. Eat better. Exercise more. Sleep more. Reduce stress. The advice is everywhere, and it's not wrong, but it's also not specific enough to produce the kind of change you're looking for.

The problem is that vascular restoration requires targeted intervention, not just general improvement. You need to know what's actually degraded, how far the degradation has progressed, and which interventions will address the specific dysfunction you're dealing with.

Eating more vegetables is helpful. But if your nitric oxide pathways are compromised because of elevated ADMA, vegetables alone won't fix it. You need the precursors that bypass the bottleneck. If your glycocalyx is stripped, Zone 2 cardio helps, but the shear stress it generates only works if you're also providing the raw materials for regeneration.

This is why protocols matter. The timing and the combination of inputs determine whether you actually move the needle.

What a Targeted Protocol Looks Like

A 90-day vascular restoration protocol typically starts with measurement. You need a baseline. What's your ADMA level? What's your hs-CRP? What does your lipid particle distribution look like? These markers (and more) tell you where the dysfunction is concentrated and how severe it is.

From there, the protocol layers in specific interventions. Some are nutritional, aimed at restoring nitric oxide production and providing the substrates the glycocalyx needs to rebuild. Some are behavioral, focused on the type of movement that generates endothelial shear stress without spiking cortisol. And some involve removing the inputs that are accelerating the damage, whether that's blood sugar volatility, sleep fragmentation, or chronic low-grade inflammation.

Every two weeks, you reassess. Not just how you feel, but what the numbers say. The goal is to see measurable change in the biomarkers, because that's what tells you whether the protocol is working.

By the end of 90 days, most men see a significant shift. Their vascular age, which is the biological age of their blood vessels compared to their chronological age, drops. Their cognitive clarity improves. Their energy stabilizes. And the symptoms that brought them in, the fog and the fatigue and the dysfunction, start to resolve because the underlying infrastructure is no longer compromised.

Why This Is Different from What You've Tried

The difference between this and what you've probably done before comes down to specificity and feedback.

When you try to improve your health on your own, you're guessing. You pick up a supplement because it sounded good. You try a new exercise routine because someone recommended it. You cut out sugar for a few weeks and hope something changes.

But without knowing what's actually broken, you can't know if what you're doing is fixing it. And without measuring the change, you can't know if it worked.

A protocol gives you both. It tells you what's wrong, targets the intervention to that specific dysfunction, and tracks whether the intervention is producing the expected result. If it's not, you adjust. If it is, you continue.

That's the difference between hoping something works and knowing it does.

What This Means for You

Vascular restoration is a measurable process with a defined timeline and specific markers of success. You don't have to accept the fog, the fatigue, or the declining performance as permanent features of your life.

Because once you see that the decline is reversible, the question becomes whether you're going to do something about it.

And for most men, by the time they're asking that question, the answer is already clear.