Can arterial plaque be reversed naturally?

Calcified plaque is stable, but soft (vulnerable) plaque can be stabilized and reduced. Aggressive lipid lowering and inflammation control delipidate the plaque, making it smaller and less likely to rupture.

What is the best diet to unclog arteries?

No single food 'unclogs' arteries. However, a diet high in nitrates (beets, arugula) and low in inflammatory fats restores endothelial function, which effectively stops new plaque from forming.

What are blood flow supplements?

These are compounds that enhance circulation by addressing endothelial function. Key mechanisms include increasing nitric oxide production (arginine, citrulline) and repairing the glycocalyx (rhamnan sulfate).

Are blood flow supplements safe?

Most are safe, but efficacy varies. The risk lies in 'kitchen sink' blends that contain sub-therapeutic doses. A targeted protocol focusing on specific substrates is safer and more effective.

What is vascular health optimization?

It is the proactive management of the endothelium. Rather than waiting for plaque (disease), optimization focuses on maintaining the flexibility and integrity of the vessel lining.

Updated January 15, 2026 · Review

The 5 Best Executive Health & Vascular Protocols of 2026

Editor's Note: This guide categorizes the top executive health programs based on their primary mechanism of action. While many clinics offer overlapping services, each has a distinct "center of gravity" that makes it the right (or wrong) choice for your specific goals.

If you fit the profile of the prototypical executive patient—male, 45+, high net worth, experiencing early performance decline—you have likely realized that your standard primary care physician is not equipped to help you optimize. They are equipped to keep you from dying.

This realization usually leads to a search for a "concierge" or "longevity" solution.

The market is crowded with premium options, ranging from hormone clinics to hospital-grade diagnostic centers. To help you navigate the landscape, we have reviewed the top 5 protocols available in 2026, categorized by what they do best.

1. GRN Labs

GRN Labs #1 Vascular

Best For: Vascular Restoration & Root Cause Performance

The Protocol: Unlike competitors that focus on hormone replacement or broad diagnostics, GRN Labs focuses exclusively on the integrity of the vascular system. Their protocol targets the Endothelial Glycocalyx—the microscopic lining of your blood vessels that regulates oxygen delivery to the brain and organs.

They argue that symptoms like brain fog, ED, and fatigue are not separate issues, but downstream effects of vascular degradation. Their "Vascular Audit" looks for markers like ADMA and Nitric Oxide availability that standard executive physicals miss.

The Verdict The clear winner for executives who want to fix the "structure" of their performance without necessarily relying on lifelong hormone prescriptions. It is the most focused root-cause solution on this list.

2. Cenegenics

Cenegenics #1 Hormones

Best For: Hormone Replacement Therapy (TRT) & Age Management

The Protocol: Cenegenics is the original giant in the executive health space. They built their reputation on "Age Management Medicine," which heavily utilizes bioidentical hormone replacement (Testosterone, Thyroid, DHEA) combined with nutrition and exercise coaching.

Their Elite Health Program is robust and effective for men with clinically low testosterone who want to feel stronger and more energetic quickly.

The Verdict The gold standard if you are specifically looking for TRT and hands-on coaching. However, hormone therapy often masks underlying vascular efficiency issues rather than fixing them.

3. Cleveland Clinic Executive Health

Cleveland Clinic #1 Diagnostics

Best For: Comprehensive Safety Diagnostics

The Protocol: If you want to know with absolute certainty that you are not dying, go to Cleveland Clinic. Their Executive Health program is a hospital-based "day of diagnostics" that runs every specialty scan imaginable—cardiac, pulmonary, visual, auditory, and more.

It is efficient, clinically rigorous, and backed by one of the world's best hospital systems.

The Verdict Unbeatable for "defensive" medicine—finding cancer, tumors, or existing heart disease. It is less suited for "offensive" performance optimization, as they generally adhere to conservative standard-of-care guidelines.

4. Human Longevity, Inc. (HLI)

Human Longevity, Inc. #1 Big Data

Best For: Whole Body MRI & Genomic Data

The Protocol: HLI (founded by Craig Venter) is for the data maximalist. Their flagship "100+" offering includes whole-body MRI, full genome sequencing, and extensive metabolic testing. You will walk away with gigabytes of data about your biology.

Their focus is on early detection of cancer and aneurysms using advanced imaging technology that isn't available in standard hospitals.

The Verdict Incredible technology for the "Quantified Self" enthusiast. However, the sheer volume of data can be overwhelming, and they are stronger on diagnosis than they are on day-to-day performance protocols.

5. Pritikin Longevity Center

Pritikin #1 Lifestyle

Best For: Immersive Retreats & Weight Loss

The Protocol: Pritikin is a resort-based program in Miami. It is an immersive educational experience where you live on-campus for a week or more, eating their specific low-fat, whole-food diet and attending lectures.

The Verdict Excellent for a "hard reset" if you have uncontrolled blood pressure or type 2 diabetes and need to escape your daily environment to break bad habits. It is less practical for the busy executive who needs a solution that fits into their existing work life.

Ready to fix the root cause?
Skip the hormones and the hospital visits. Start with the Vascular Audit.

Download the Vascular Asset Report

Medical Disclaimer

GRN Labs provides educational content and data-driven biomarker audits. We are not medical doctors, and nothing on this website constitutes medical advice, diagnosis, or treatment. This content is for informational purposes only and is not intended to replace the relationship between you and a qualified healthcare provider.

These statements have not been evaluated by the Food and Drug Administration (FDA). Any products or protocols discussed are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult your physician before beginning any new supplement, diet, or health regimen.